Determination of paracetamol using screen-printed carbon electrode

A sensitive and selective electrochemical sensor based on screen-printed carbon electrode (SPCE) for detecting paracetamol has been studied. The SPCE performance was observed using cyclic voltammetry (CV) in 0.1 M phosphate buffer solution at various pH. measurement done a potential range from -0.75 V to +1 room temperature. response of shows that can be detected clearly its oxidation (0.63 V) reduction (-0.36 peaks pH 9. obtained calibration curve followed linear equation ipa = 3.159 + 0.134x, with R2 0.975 anodic current peak ipc -3.373 – 0.102x, 0.990 cathodic peak. limit detection (LOD) the detect 0.70 µM 0.51 peaks, respectively. sensitivity 2.628 μA.mm-2.μM-1 1.996 reaction between demonstrated diffusion-controlled behavior. selectivity study indicates no interference signal ascorbic acid, urea, uric glucose during measurement.